泰国儿童严重登革热的胃肠道表现和预后因素
Kittiya Setrkraising1, Chatporn Kittitrakul2
1Department of Pediatrics, Charoenkrung Pracharak Hospital, Bangkok, Thailand.
The American journal of tropical medicine and hygiene
|December 24, 2024
概括
胃肠道症状如厌食症和吐在登革热儿童中很常见. 吐,,和特定的实验室值预测严重的登革热,需要密切监测儿科患者.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 登革热是热带地区的主要公共卫生问题,特别影响泰国的5-14岁儿童.
- 胃肠道 (GI) 症状在登革热感染中经常被观察到,可能会使儿科患者的诊断和管理复杂化.
研究的目的:
- 为了确定患有登革热的儿童中胃肠道症状的患病率.
- 确定与儿科患者严重登革热感染相关的预后因素.
主要方法:
- 对2019-2022年登革热感染住院的儿童 (0-14岁) 的医疗记录的回顾性审查.
- 登革热严重程度的分类基于2009年世卫组织指南.
- 后勤回归分析,以评估临床/实验室数据与严重登革热之间的关联.
主要成果:
- 在556例登革热病例中,8.6%是严重的. 常见的胃肠道症状包括厌食症 (91.7%),吐 (57.6%) 和腹痛 (38.3%).
- 吐,,AST>450 U/L,血清白蛋白低 (<3.5 g/dL) 与严重登革热有显著联系.
- 年龄较小的儿童 (<5岁) 呈现的典型胃肠道症状较少,这给诊断带来了挑战.
结论:
- 胃肠道表现在儿科登革热中很普遍,特定的症状和实验室发现表明严重疾病的风险更高.
- 密切监测对于患有登革热的儿童具有吐,,或异常的肝酶和白蛋白水平至关重要,以防止严重的后果.
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