在死亡性外耳炎 (NOE) 中接受系统性抗生素治疗之前
Sharifah Sara Syed Badrol1, Oren Ziv2,3, Chilaf Peled4
1Department of Otolaryngology-Head and Neck Surgery, Worcestershire Royal Hospital, Worcestershire, UK.
概括
服用前的抗生素不会改变导致外耳死 (NOE) 的细菌类型,也不会影响疾病的严重程度. 在NOE中的无菌培养可能是由于拭子限制造成的,这表明需要深层组织采样.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 微生物学 微生物学
背景情况:
- 外耳垂死性耳炎 (NOE) 是一种严重的感染,主要是由Pseudomonas aeruginosa引起的.
- 对Pseudomonas aeruginosa的系统性抗生素使用显著增加.
- 已经观察到NOE引起病原体的转移趋势.
研究的目的:
- 确定服用前的抗生素治疗是否会影响NOE中的病原体和无菌培养的发生率.
- 评估服用前抗生素对NOE严重程度和疾病进展的影响.
主要方法:
- 对因NOE入院的患者进行了回顾性病例系列分析.
- 包括所有被录取到单一第三级护理中心的患者.
主要成果:
- 分析了83名患者;17人没有接受过先前的抗生素,65人接受了入院前的抗生素.
- 在病原体发生率或无菌培养率方面,两组之间没有发现显著差异.
- 住院时间,外科干预和再入院率在不同组中相似.
结论:
- 服用前的抗生素治疗不会改变NOE中致病原体的谱或无菌培养率.
- 抗生素预治疗不会影响NOE疾病的严重程度或进展.
- 无菌培养可能是由于拭子敏感性低;深层组织培养是建议NOE患者.
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