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Updated: May 8, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Published on: January 7, 2019

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准胰岛素样生长因子-1受体,以克服慢性髓性白血病中伊马替尼抗性

Seiichi Okabe1, Yuya Arai2, Akihiko Gotoh2

  • 1Department of Hematology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-Ku, Tokyo, 160-0023, Japan. okabe@tokyo-med.ac.jp.

Discover oncology
|December 24, 2024
PubMed
概括

胰岛素样生长因子1 (IGF-1) 途径有助于慢性髓性白血病 (CML) 中的伊马替尼抗性. 使用林西提尼布抑制IGF-1受体 (IGF-1R) 有望在CML患者中克服这种耐药性.

关键词:
慢性骨髓性白血病 慢性骨髓性白血病对伊马替尼布产生抗药性胰岛素类生长因子-1受体抑制剂

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