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在患有左心室缩功能障碍的门诊患者中,TAPSE与PASP比率的预后作用

Mauro Riccardi¹, Matteo Pagnesi¹, Rossana Corso²

¹Department of Medical and Surgical Specialties, Radiological Science and Public Health, Institute of Cardiology, ASST Spedali Civili, University of Brescia, Brescia, Italy.

ESC heart failure

|December 25, 2024

概括

三环平面对肺动脉缩压 (TAPSE/PASP) 的缩外流与心力衰竭患者的结果有关. 较低的TAPSE/PASP比率预测死亡率和心力衰竭事件的增加,突出其预后价值.

科学领域:

心脏病学心脏病学
心血管生理学心血管生理学
心脏衰竭研究研究

背景情况:

有限的数据存在于预后价值的三管环平面缩外游到肺动脉缩压力 (TAPSE/PASP) 在慢性心力衰竭与左心室缩功能障碍.
TAPSE/PASP量化了右心室与肺动脉的合,这是心脏功能的一个关键方面.

研究的目的:

调查TAPSE/PASP与左心室缩功能障碍患者的不良结果 (全因死亡率或心力衰竭事件) 之间的关联.
评估TAPSE/PASP作为连续变量,并通过三位数来预测临床结果.

主要方法:

在2022年1月至2022年12月期间,对642名左心室喷射率≤50%的门诊患者进行了回顾性单中心研究.
在基线评估TAPSE/PASP,并将患者分为三级.
主要结局是所有原因死亡率或心力衰竭事件的复合,随访时间中位数为474天.

主要成果:

最低TAPSE/PASP三位数的患者有更多的并发症,较高的NYHA类,并增加了拥堵的迹象.
在最低的TAPSE/PASP第三层 (38.0%) 与中间 (19.6%) 和最高 (14.9%) 的第三层 (P < 0.001) 相比,主要结果的1年率显著更高.
TAPSE/PASP与主要结果独立相关 (aHR为0.91每0.1mm/mmHg增加,P=0.009),主要是由HF事件驱动的.

结论:

TAPSE/PASP是左心室缩功能障碍的门诊患者死亡率和心力衰竭事件的独立预测器.
较低的TAPSE/PASP比率表明预后较差,强调其在风险分层中的临床实用性.

关键词:

心脏衰竭是因为心脏衰竭.门诊患者门诊患者这里是 PASP PASP.这就是TAPSE.TAPSE.

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