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通过基于结构的优化为治疗开发的新型FGF21类似物

Yiqing Guo1, Yuxuan Bao2, Zhichao Chen2

  • 1Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.

Acta biochimica et biophysica Sinica
|December 25, 2024
PubMed
概括

研究人员通过将FGF21与Fc片段融合而开发出长期起作用的纤维细胞生长因子21 (FGF21) 类似物. 这些新型类似物显示出增强的功效,为肥胖和相关代谢障碍提供了潜在的新疗法.

关键词:
纤维细胞生长因子21 (FGF21)代谢性疾病是代谢性疾病.蛋白质工程工程 蛋白质工程序列分析分析的序列分析.

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