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Updated: Jun 4, 2025

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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I型干扰素和线粒体功能障碍与青少年系统性红血狼中失调的细胞毒性CD8+T细胞反应有关

Anna Radziszewska1,2, Hannah Peckham1,2, Restuadi Restuadi1,3

  • 1Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH, GOSH, London, UK.

Clinical and experimental immunology
|December 25, 2024
PubMed
概括

青少年系统性红斑狼 (JSLE) 患者由于线粒体功能障碍和I型干扰素信号增强而表现出降低的CD8+T细胞细胞毒性. 这会影响效能记忆T细胞,导致JSLE的发病.

关键词:
CD8+ T 细胞 CD8+ T 细胞细胞毒性 细胞毒性干扰子干扰子干扰子青少年系统性红血性狼

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