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Updated: May 8, 2025

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9
08:14

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9

Published on: August 28, 2018

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目前的证据和PCSK9抑制的未来方向

Jiaqian Xu1, Michael D Shapiro1

  • 1Center for the Prevention of Cardiovascular Disease, Section on Cardiovascular Medicine, Wake Forest University Baptist Medical Center Winston Salem, NC.

US cardiology
|December 25, 2024
PubMed
概括

新的proprotein转化酶抑制剂 (PCSK9) 提供了先进的高胆固醇血症管理. 这些疗法,包括单克隆抗体和siRNA,有效降低LDL胆固醇,特别是在对他类药物不耐受的患者中.

关键词:
动脉样硬化心血管疾病.这就是为什么LDL胆固醇是LDL胆固醇.超高胆固醇血症是一种高胆固醇血症.蛋白转化酶亚提利辛/凯类型9沉默RNA是为了使RNA沉默.

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