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Updated: May 8, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

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Published on: August 21, 2016

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性别偏差的CD3ζ 3'-UTR SNP增加了无形成性贫血的发病风险

Lixing Guo1, Yuping Zhang2, Xiaoen Liu3

  • 1Department of Hematology and Oncology, The Fifth Affiliated Hospital of Jinan University, Heyuan, People's Republic of China.

International journal of general medicine
|December 25, 2024
PubMed
概括

这项研究在CD3ζ3'-未翻译区域 (3'-UTR) 中确定了与无塑性贫血 (AA) 易感性相关的性别特异单核酸多态 (SNPs). 一个SNP,rs3738212,被发现可以调高CD3ζ蛋白水平,为AA病原体提供了新的见解.

关键词:
CD3ζ 3′-没有翻译的区域.CD3ζ 蛋白质的水平.没有无形性贫血.单核酸多形态的单核酸多形态

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