在非洲南部接受治疗的结核病患者中的心血管参与
Daryoush Samim1, Guy Muula2, Nicolas Banholzer3
1Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
JACC. Advances
|December 25, 2024
概括
结核病 (TB) 经常导致心脏问题,特别是心脏周围的溢出和加厚. 结核病的治疗可以逆转这些早期的心脏变化,突出显示了心声回声学对早期检测和管理的重要性.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 结核病 (TB) 是全球主要的死亡原因,特别是在艾滋病毒感染者中.
- 结核病的亚临床心血管并发症在高负担地区的研究不足.
- 了解结核病对心脏的影响对于公共卫生倡议至关重要.
研究的目的:
- 为了确定结核病患者心血管疾病的患病率.
- 评估抗结核治疗后心脏状况的变化.
主要方法:
- 跨胸腔心声扫描 (TTE) 用于评估在赞比亚和南非的286名结核病患者 (HIV阳性和HIV阴性).
- 结核病诊断时和6个月治疗后进行了心脏评估.
- 分析的重点是心周溢出,加厚,化和收缩.
主要成果:
- 在诊断时,47%的结核病患者患有心周溢血,30%患有结结.
- 在结核病治疗后,心周液从47%降至16% (P < 0.001),心周液从30%降至15% (P = 0.002).
- 在治疗前和治疗后,心周结石和收缩症状保持相似.
结论:
- 新确诊的结核病患者中心脏参与,特别是心周异常,是常见的.
- 与结核病相关的早期心周变化可以通过成功的抗结核治疗来逆转.
- 心声图对于检测和管理结核病患者心血管并发症有价值.
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