慢性胰腺炎作为胰腺癌的驱动因素:流行病学理解
Amlan Das1, Akash Bararia2, Sanghamitra Mukherjee3
1Department of Biochemistry, Royal Global University, Guwahati 781035, India.
World journal of clinical oncology
|December 25, 2024
概括
慢性胰腺炎 (CP) 的住院病例正在增加,存在显著差异. 超重的黑人男性和收入较高的40岁以上的白人男性在CP患者中面临胰腺癌 (PDAC) 风险升高.
科学领域:
- 胃肠道学和瘤学
- 公共卫生和流行病学
背景情况:
- 慢性胰腺炎 (CP) 的住院率不断上升,需要了解相关风险和差异.
- 胰腺管道腺癌 (PDAC) 是CP患者的一个重大问题.
研究的目的:
- 检查CP住院的趋势.
- 确定与CP和PDAC相关的风险因素和种族差异.
- 调查医疗保健获取和利用的影响.
主要方法:
- 这是一项回顾性研究,分析了2016-2017年1420万名入学者的情况.
- 多变量回归分析以确定CP患者中CP和PDAC的风险因素.
主要成果:
- 2.6%的成年患者患有脑膜炎;白人男性占多数.
- 在男性,黑人,年龄在40-59岁之间以及BMI在25-29.9.9之间的人群中观察到CP风险增加.
- 0.78%的CP患者也患有PDAC;年龄较大和BMI是PDAC的重要风险因素.
结论:
- 在CP和PDAC风险和结果方面存在显著的种族差异.
- 超重的40-59岁的黑人男性和高收入的40岁以上的白人男性在CP患者中患有PDAC风险较高.
- 获得和利用医疗保健的差异可能会影响CP和PDAC的风险和结果.
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