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细胞外酸化刺激OGR1通过Ca2+-氨酸-NFATc1通路改变骨质细胞分化和活性

Feng-Bo Li1, Su-Qing Bao2, Xiao-Lei Sun1

  • 1Department of Orthopedics, Tianjin Hospital, Tianjin 300211, P.R. China.

Experimental and therapeutic medicine
|December 25, 2024
PubMed
概括

细胞外酸性增强骨质细胞分化和骨质再吸收,卵巢癌G蛋白结合受体1 (OGR1) 起着关键作用. OGR1调解 (Ca2+) 的升高,这对于骨质细胞中的Ca2+-氨酸-NFATc1信号通路至关重要.

关键词:
这是一种酸性症.骨质结晶体的骨质细胞.卵巢癌G蛋白结合受体1 卵巢癌G蛋白结合受体1质子感应受体是一种感应受体.

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