运动在肥胖性肝病中的作用:一个更新的视角
Iyiad Alabdul Razzak1, Ahmed Fares2, Jonathan G Stine3,4
1Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
概括
运动对于管理与代谢功能障碍相关的脂肪性肝病 (MASLD) 至关重要,即使在晚期肝硬化中也能带来好处. 为所有患者推个性化炼计划,以及新兴疗法.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 运动生理学 运动生理学
- 代谢疾病 代谢疾病
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,随着久坐不动的生活方式而上升.
- MASLD是最常见的脂肪性肝病 (SLD),是全球慢性肝病的主要原因.
- 运动对于MASLD管理至关重要,即使是新的药物选择.
研究的目的:
- 审查运动在控制脂肪性肝病 (SLD) 中的作用.
- 突出运动在SLD中的分子和临床益处.
- 评估运动对肝硬化患者的益处和安全性.
主要方法:
- 对运动和SLD进行的临床前和临床研究的审查.
- 评估运动对晚期慢性肝病的影响.
- 在resmetirom和incretins等新疗法背景下对运动的分析.
主要成果:
- 运动是MASLD治疗的基石.
- 运动的好处延伸到肝硬化患者.
- 建议所有MASLD患者,包括服用药物的患者进行个性化炼.
结论:
- 运动对于MASLD的管理至关重要,包括肝硬化.
- 量身定制的运动计划对于所有患者来说都是必不可少的.
- 需要进一步的研究来优化炼方案,并探索与新疗法的协同效应.
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