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Updated: May 8, 2025

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
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Published on: February 10, 2023

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PairK:双向k-mer对齐用于量化无序区域中的蛋白质基因保护

Jackson C Halpin1, Amy E Keating1,2,3

  • 1Department of Biology, MIT, Cambridge, Massachusetts, USA.

Protein science : a publication of the Protein Society
|December 25, 2024
PubMed
概括

我们开发了PairK,这是一种新的方法,可以准确地测量内在无序区域 (IDR) 中短线性图案 (SLiM) 的进化保存. PairK的性能优于现有的工具,揭示了功能性SLiM的更深层次的保护,远远超过之前的想法.

关键词:
保护 保护 保护本质上是无序的蛋白质.多个序列对齐的多重序列对齐.一个简短的线性图案.

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