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Updated: Jun 4, 2025

mirMachine: A One-Stop Shop for Plant miRNA Annotation
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基于链位移放大器的双放大单颗粒ICP-MS策略-CRISPR/Cas12a放大器用于对miRNA的均检测

Yan Xu1, Beibei Chen1, Man He1

  • 1Department of Chemistry, Wuhan University, Wuhan 430072, China.

Analytical chemistry
|December 25, 2024
PubMed
概括

本研究提出了一种使用金纳米粒子和CRISPR/Cas12a技术检测microRNA-21的敏感方法. 该试验为癌症诊断中识别生物标志物的新方法提供了新的方法.

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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