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Updated: Jun 4, 2025

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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通过途径分析和CYP1B1突变的功能性表征,初级先天性玻璃眼的功能性基因组学

Muneeb A Faiq1, Himanshu N Singh2, Mashooq Ali3

  • 1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India; Medical Biotechnology Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi 110007, India; Laboratory of Molecular Genetics and Reproduction, Department of Anatomy, All India Institute of Medical Sciences, New Delhi 110029, India; Department of Radiology, NYU Grossman School of Medicine, New York University, New York, NY 10016, USA; Department of Ophthalmology, NYU Grossman School of Medicine, New York University, New York, NY 10017, USA; Tech4Health Institute, NYU Grossman School of Medicine, New York University, Long Island City, NY 11101, USA.

Vision research
|December 25, 2024
PubMed
概括

CYP1B1基因的突变破坏了重要的新陈代谢途径,如雌激醇和视网代谢,导致儿童的初级先天性玻璃眼 (PCG). 了解这些机制对于开发这种常见的儿童眼部疾病的新疗法至关重要.

关键词:
在CYP1B1B1中.功能性基因组学是一种功能性基因组学.眼光障碍 眼光障碍 眼光障碍 眼光障碍眼睛的发展 眼睛的发展病变的发生和发病.路径分析 路径分析主要的先天性玻璃眼.反应原子是如何反应的

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