听力损失的儿科骨骨折的长期结果:多国数据库分析结果
Jason L Steele1, Heather J Smith2, Samira Takkoush3
1University of Utah, Department of Otolaryngology - Head & Neck Surgery, United States; Rocky Vista University College of Osteopathic Medicine, United States.
International journal of pediatric otorhinolaryngology
|December 25, 2024
概括
儿童骨骨折 (TBFs) 与听力损失显著增加脑膜炎和面部神经疾病的风险. 这些损伤也可能会增加儿童患迷宫炎,脑脊液泄漏和耳植入的可能性.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 神经外科 神经外科
- 创伤外科 手术 创伤外科
背景情况:
- 儿童骨骨折 (TBF) 与严重的并发症有关,如脑膜炎,需要耳植入 (CI) 的听力损失,面部神经衰弱,脑脊液 (CSF) 泄漏和迷宫炎.
- 了解患有听力损失的儿科TBF患者这些结果的特定风险对于有效的管理至关重要.
研究的目的:
- 确定患有脑膜炎,CI,面部神经疾病,脑脊髓液泄漏和迷宫炎的风险,在患有TBF和听力损失的儿科患者中.
- 将这些风险与没有结核病的儿科患者相匹配的队列进行比较.
主要方法:
- 一项回顾性队列研究利用了跨国TrinetX数据库.
- 确定了儿科患者 (<18岁) 头骨底部骨折和听力损失的诊断代码作为TBF的代理.
- 选择了年龄和性别匹配的对照组;用于计算风险比率,应用了1:1的倾向性得分匹配 (PSM).
主要成果:
- 这项研究包括2739名患有TBF的儿科患者和2739名对照患者.
- 儿科TBF患者出现脑膜炎 (RR:2.90) 和面部神经疾病 (RR:13.44) 的风险显著增加.
- 在TBF队列中,PSM前分析表明迷宫炎 (RR: 43.12),CI (RR: 21.61) 和CSF泄漏 (RR: 89.08) 的风险大幅增加.
结论:
- 听力损失的儿科TBF增加了随后脑膜炎和面部神经疾病的风险.
- 在这些儿科患者中,可能会增加迷宫炎,脑脊液泄漏和需要耳植入器的风险.
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