SymScore:机器学习准确度在基于符号回归的临床分数生成器中满足透明度
Olive R Cawiding1, Sieun Lee2, Hyeontae Jo3
1Department of Mathematical Sciences, KAIST, Daejeon, 34141, Republic of Korea; Biomedical Mathematics Group, Pioneer Research Center for Mathematical and Computational Sciences, Institute for Basic Science, Daejeon, 34126, Republic of Korea.
Computers in biology and medicine
|December 25, 2024
概括
本研究介绍了SymScore,这是一种工具,可以为缩短的临床调查问卷创建可解释的得分表. 在不需要机器学习专业知识的情况下,SymScore提供了准确的疾病风险评估,提高了临床信任和效率.
科学领域:
- 医疗信息学 医疗信息学
- 医疗保健中的人工智能
- 临床决策支持 临床决策支持
背景情况:
- 自我报告问卷对于疾病风险评估至关重要,但冗长的问卷可能会影响数据质量.
- 机器学习 (ML) 缩短的问卷提供了准确性,但缺乏透明度,需要专门的专业知识,阻碍了临床采用.
- 医疗保健专业人员需要可解释的工具,以便在临床工作流程中获得信任和有效的决策.
研究的目的:
- 开发一种新的方法,SymScore,为缩短的临床问卷生成可解释的得分表.
- 在风险评估工具中保持预测准确性和临床解释性.
- 为医疗保健专业人员提供一个用户友好的替代复杂的ML模型.
主要方法:
- SymScore使用符号回归来生成缩短问卷的得分表.
- 它以最佳方式分组响应,根据预测重要性分配权重,并应用约束.
- 对睡眠障碍评估的表现与已建立的基于ML的缩短问卷 (MCQI-6,SLEEPS) 进行了比较.
主要成果:
- 符号SymScore的表现与MCQI-6的表现相似 (MAE=10.73,R2=0.77与MAE=9.94,R2=0.82).
- 在睡眠障碍方面达到高AUROC值 (0.85-0.91),与SLEEPS (0.88-0.94) 非常接近.
- 生成可解释的分数表,临床医生可以很容易地理解和信任.
结论:
- 通过使用缩短的问卷,SymScore为临床风险评估提供了准确和可解释的解决方案.
- 它通过弥合预测准确性和临床可用性之间的差距,在医疗保健中推进了可解释的AI.
- 通过为临床医生提供资源效率高,可信赖的工具,SymScore提高了工作流效率和患者的结果.
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