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Updated: Jun 4, 2025

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
09:20

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS

Published on: August 10, 2017

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在急性髓性白血病中,c-JUN 与HDAC1相互作用,作为潜在的组合治疗点

Ke Wu1, Xiaoyu Xu2, Wei Wei1

  • 1Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.

International immunopharmacology
|December 25, 2024
PubMed
概括

这项研究表明,用Ailanthone和Panobinostat抑制c-JUN和HDAC1可以有效地治疗小鼠模型中的急性髓性白血病 (AML). 这种组合疗法在AML治疗中显示出有前途,具有安全性.

关键词:
患有急性髓性白血病的人.组合疗法是一种联合疗法.在 HDAC1 中,HDAC1 是门德尔的随机化一个单细胞RNA-seqq.在c-JUN.

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