体质指数变化与老年腹腔透析患者的死亡率之间的关系:一个病例对照研究
Yelda Deligoz Bildacı1, Berfu Korucu2, Mehmet Ası Oktan2
1Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Dokuz Eylul University, Izmir, Turkey. yelda.deligozbildaci@deu.edu.tr.
BMC nephrology
|December 25, 2024
概括
在腹腔透析 (PD) 的老年人中,在开始治疗后体重指数 (BMI) 的下降与更糟糕的生存结果有关. 定期的BMI监测可以帮助预测这些患者的预后.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年医学 老年医学
- 内部医学 内部医学
背景情况:
- 慢性病 (CKD) 的患病率在全球范围内正在上升,特别是在65岁以上的人群中.
- 替代疗法 (RRT) 患者的蛋白质能量浪费与增加的发病率和死亡率有关.
- 人口老龄化需要了解老年慢性病患者的特定健康挑战.
研究的目的:
- 调查身体质量指数 (BMI) 变化与接受腹腔透析 (PD) 的老年患者的存活率之间的关联.
- 确定BMI趋势是否预测PD末期病老年人的结果.
主要方法:
- 从1998年到2022年,对发生的成人PD患者进行了回顾性,单中心研究.
- 分析的重点是老年患者 (≥65岁) 患有PD开始后的BMI变化记录.
- 基于BMI轨迹的生存结果的比较.
主要成果:
- 在透析开始后降低的BMI与老年PD患者的存活率之间观察到显著的负相关性 (p=0.01).
- 体重指数对生存的负面影响独立于其他危险因素,如糖尿病,心血管疾病,性别,残留功能和先前的血液透析 (p=0.04).
结论:
- 虽然不是一个完美的指标,但定期的身体质量指数 (BMI) 监测对于评估老年透析患者的预后非常有价值.
- 追踪老年PD患者的BMI变化可以作为指导患者管理和预测结果的关键指标.
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