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Updated: Jun 4, 2025

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一个I期剂量确定设计,包括患者内剂量升级

Beibei Guo1, Suyu Liu2

  • 1Department of Experimental Statistics, Louisiana State University, Baton Rouge, Louisiana, USA.

Pharmaceutical statistics
|December 26, 2024
PubMed
概括

本研究为I期试验引入了患者内剂量升级持续重新评估方法 (IP-CRM). IP-CRM设计有效地识别了最大耐受剂量 (MTD),采用较小的样本大小,改进了传统方法.

关键词:
这就是为什么CRM是CRMCRM.第一个阶段I阶段转载过来的时间.发现剂量发现剂量在患者内治疗.

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