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Updated: May 8, 2025

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CryptKeeper:一种负面设计工具,用于减少细菌中的无意基因表达

Cameron T Roots1, Jeffrey E Barrick1

  • 1Department of Molecular Biosciences, Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712, USA.

Synthetic biology (Oxford, England)
|December 26, 2024
PubMed
概括

CryptKeeper软件可以从大肠杆菌中的合成DNA序列中预测意外的基因表达. 这种工具有助于研究人员避免分子生物学和合成生物学应用中的遗传不稳定性和实验失败.

关键词:
计算的DNA序列设计设计.设计 - 建造 - 测试周期.质粒的不稳定性 质粒不稳定性再组合蛋白过度表达的情况.可靠性和可重复性.

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