患有缺铁性贫血的患者的胃肠道病理:一个单中心的横截面研究
Shaik Mohammad Tahaseen1, Ravi Kirti1, Ramesh Kumar2
1Department of General Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.
印度成年人的缺铁性贫血 (IDA) 通常表明显著的胃肠道 (GI) 病理,包括恶性瘤. 早期内镜检查对于有风险的人来说至关重要,特别是40岁以上有特定症状的男性.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 在瘤学瘤学.
背景情况:
- 缺铁性贫血 (IDA) 影响全球人口的很大一部分,缺铁是主要原因.
- 了解胃肠道 (GI) 病理的患病率,特别是恶性瘤,对于IDA患者的早期诊断和治疗至关重要.
研究的目的:
- 估计具有显著的胃肠道病理,包括胃肠道恶性瘤的IDA患者的比例.
- 确定与IGD患者的肠道病理和恶性瘤相关的风险因素和预测因素.
主要方法:
- 一项涉及成年男性和绝经后女性的横截面研究,与印度东部的IDA.
- 数据收集包括详细的病史,饮食习惯,胃肠道症状和贫血严重程度.
- 进行了便隐性血液测试 (OBT) 和用活检进行上/下肠道内镜检查.
主要成果:
- 超过50%的IDA患者表现出显著的GI病理,其中25.68%被诊断为GI恶性瘤.
- 胃肠道病理的独立风险因素包括男性性别和阳性OBT.
- 胃肠道恶性瘤的危险因素包括年龄≥40,食欲丧失,腹痛,消化不良,恶性瘤家族病史和阳性OBT.
结论:
- 印度有大量的成年男性和绝经后女性患有IDA,存在显著的胃肠道病理,包括恶性瘤.
- 建议对这些患者进行双向内镜检查.
- 优先调查男性患者,40岁以上的患者,有特定症状 (食欲/体重减轻,腹痛,消化不良),家族病史,并呈阳性OBT.
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