探索饮食植物化学指数和化疗相关症状之间的关系:从一个横截面研究的见解
Barış Yüksel1, Gözde Dumlu Bilgin2, Hasan Kaan Kavsara2,3
1Department of Nutrition and Dietetics Yeditepe University, Institute of Health Sciences Istanbul Türkiye.
Food science & nutrition
|December 26, 2024
概括
饮食中摄入更多的植物化学品与减少化疗副作用有关. 这项研究发现,增加饮食中的植物化学物质可能有助于在接受化疗的癌症患者中管理与治疗有关的症状.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 癌症症状管理 癌症症状管理
背景情况:
- 化疗往往会导致使人衰弱的症状,影响患者的生活质量.
- 植物化学物质,植物衍生化合物,以其潜在的健康益处而闻名,包括抗炎和抗氧化特性.
研究的目的:
- 调查饮食中植物化学品摄入量与化疗相关症状的严重程度之间的关联.
- 为了确定饮食中的植物化学物质是否可以帮助缓解癌症患者治疗副作用.
主要方法:
- 一项涉及152名化疗患者的横截面研究.
- 收集的数据包括人口统计,人体测量,三天的食物记录和夜症状评估量表 (N-SAS).
- 饮食生化指数 (DPI) 根据DPI四分位数的N-SAS得分计算和分析.
主要成果:
- 随着DPI四分位数的增加 (p=0.002),观察到N-SAS得分的统计显著下降.
- 在所有癌症类型中,N-SAS得分和DPI之间发现了显著的负相关性 (r=-0.364;p<0.001).
- 对于特定的癌症也注意到了负相关性:肺癌 (r=-0.513; p=0.005),乳腺癌 (r=-0.612; p<0.001) 和胃肠道系统癌 (r=-0.329; p=0.033).
结论:
- 饮食中增加的植物化学品摄入量与减少化疗相关症状有关.
- 饮食中的植物化学物质显示出作为一种有希望的支持策略,用于管理癌症患者治疗副作用.
- 对植物化学物质的饮食干预措施进行进一步的研究是有必要的,以优化癌症护理.
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