骨髓瘤切除后管理伤口并发症:停止辅助治疗并进行二次关闭
Kiichi Furuse1, Daisuke Kageyama2, Masaki Arikawa2
1Plastic and Reconstructive Surgery, National Cancer Center Hospital East, Chiba, JPN.
Cureus
|December 26, 2024
概括
骨髓瘤 (OS) 手术后的辅助化疗 (AC) 可以使伤口愈合复杂化. 暂时暂停AC并进行伤口关闭可以帮助管理并发症,同时完成治疗并保存肢体.
科学领域:
- 在瘤学瘤学.
- 整形外科手术 整形外科手术
- 癌症治疗方法 癌症治疗方法
背景情况:
- 辅助化疗 (AC) 是骨髓瘤 (OS) 节约四肢手术后的标准.
- AC可以对伤口愈合产生负面影响,冒着内脏假体暴露的风险.
- 在AC期间管理伤口并发症对于肢体救援至关重要.
研究的目的:
- 制定骨髓瘤切除和内膜假体植入后的伤口并发症管理指南.
- 评估暂时暂停AC对伤口愈合和治疗完成的影响.
- 评估完成AC和成功的肢体救援策略之间的平衡.
主要方法:
- 这是一项对22名患有原发性骨髓瘤的患者进行的观察性回顾性研究.
- 分析局部伤口发现,AC协议,并发症和生存率.
- 对有伤口并发症和没有伤口并发症的患者之间的结局进行比较.
主要成果:
- 41%的患者 (9/22) 经历了伤口并发症.
- 在大多数情况下,临时的交流暂停,脱bridement和二次关闭允许完成AC.
- 在患有和没有伤口并发症的患者之间,从手术到AC完成的持续时间没有显著差异 (p=0.648).
结论:
- 骨髓瘤手术后伤口并发症的有效管理包括平衡AC完成与肢体救援.
- 迅速暂停AC和手术伤口管理至关重要.
- 这种方法有助于完成辅助化疗和成功保存肢体.
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