微塑料在紫外线消毒过程中加剧了抗生素耐药性基因的结合转移:突出了传统和可生物降解基因之间的差异
Xinrui Zhang1, Jian Wang2, Zeyuan Yang1
1Key Laboratory of Plant Nutrition and the Agro-Environment in Northwest China, Ministry of Agriculture and Rural Affairs, College of Natural Resources and Environment, Northwest A & F University, Yangling, Shaanxi 712100, China.
Environmental science & technology
|December 26, 2024
概括
微塑料 (MP) 在废水处理过程中增强抗生素耐药性基因 (ARG) 转移. 传统和可生物降解的MP都促进了这一过程,聚乙烯MP由于碎片化和ROS生产而表现出更大的效果.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 环境化学环境化学
背景情况:
- 微塑料 (MP) 是废水中抗生素耐药性基因 (ARG) 的已知储库.
- 议员在废水处理过程中对ARG转移的影响尚不清楚.
研究的目的:
- 研究常规 (聚乙烯,PS) 和生物降解 (聚乳酸,PLA) MPs在ARG的结合性转移中的作用.
- 阐明MPs在紫外线 (UV) 消毒过程中影响ARG转移的机制.
主要方法:
- 在紫外线消毒过程中对PS和PLAMP进行比较研究.
- 分析不同条件下的ARG转移率.
- 研究MP碎片化,活性氧物种 (ROS) 生产和细菌反应.
主要成果:
- 与单独的紫外线消毒相比,MPs显著促进了ARG的结合性转移.
- 聚烯MP显示了比PLAMP更高的促进效应.
- 促进机制包括光屏蔽,ROS生产和纳米塑料生成,这增加了细菌的氧化应激和细胞间接触.
结论:
- 传统的和可生物降解的MP都对废水处理中的ARG转移构成风险.
- 将MP碎片化成纳米塑料和ROS生成是增强ARG交换的关键机制.
- 了解这些综合风险对于环境风险评估至关重要.
相关概念视频
Physical Methods for Controlling Microbial Growth: Radiation and Filtration
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
Bacterial Transformation
55.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
55.1K
Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Antibiotic Selection
52.3K
Overview
52.3K
Biological Methods for Microbial Control
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
Genomic DNA in Prokaryotes
43.4K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.4K


