在完整的鼻或先前有大膜穿孔的鼻中,鼻地板升高后骨再生:使用子鼻模型进行临床前研究
Sunmin Lee1, Jong-Hyuk Chung2, Daniel S Thoma3
1Department of Dentistry, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Journal of clinical periodontology
|December 26, 2024
概括
经过先前大鼻膜穿孔的鼻地板升高 (SFE) 显示了与完整的鼻相比的骨再生. 在SFE手术中,穿孔后的愈合不会影响新的骨形成.
科学领域:
- 口腔和牙面部外科手术
- 牙周病学 牙周病学
- 再生医学是一种再生医学.
背景情况:
- 阴道床升高 (SFE) 是一种常见的程序,用于增强后大骨.
- 在SFE期间,阴道膜完整性往往是一个问题,穿孔可能会影响结果.
- 了解SFE后的骨再生与先前的膜穿孔对于可预测的结果至关重要.
研究的目的:
- 为了评估和比较SFE后的骨再生,在子模型中,先前有或没有大鼻膜穿孔.
- 评估穿孔后8周愈合期对后续SFE骨形成的影响.
主要方法:
- 在子鼻膜中有意造成大孔 (≥5毫米),用原基质处理,并允许在8周内愈合.
- 在穿孔和完整的鼻中进行了 sinus floor elevation.
- 在SFE后的2周和4周进行了微计算机断层扫描和组织形态测量分析.
主要成果:
- 在第2周和第4周,在穿孔和完整的鼻组之间没有观察到在增强区域内新形成的骨总量的显著差异.
- 与穿孔组相比,在完整的鼻组中,在鼻膜中间附近形成的新骨的数量显著增加.
- 增加的体积保持一致,但穿孔组显示出较少的亚皮质腺体和 sinus 膜中更密集的原纤维.
结论:
- 经过8周的愈合期后的大型鼻膜穿孔不会对鼻底升高后的整体新骨形成产生负面影响.
- 这些发现表明,即使在严重的鼻膜损伤后,也可以成功地进行SFE,只要有足够的愈合时间.
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