亚洲印第安患者的眼皮黑色素细胞病变:流行率,临床表现,以及与冠状腺黑色素瘤的关联
Prapti Chheda1, Srishti Ramamurthy1, Vishal Raval1,2
1Anant Bajaj Retina Institute, Hyderabad, Telangana, India.
Indian journal of ophthalmology
|December 26, 2024
概括
眼部 (皮肤) 黑色素细胞瘤 (ODM) 在亚洲印第安人中很少见,但会增加患冠状腺黑色素瘤 (CM) 的风险. 定期的眼科检查对于在MDM患者中早期发现CM至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 眼部 (皮肤) 黑色素细胞症 (ODM) 是一种先天性疾病,其特征是眼部和皮肤组织中的黑色素沉积.
- 人们已经认识到ODM与胆管黑色素瘤 (CM) 之间的关联,但特定人群的患病率和风险因素需要进一步研究.
研究的目的:
- 确定亚裔印度患者中ODM的流行率.
- 研究ODM的临床表现,治疗和随访.
- 评估该人群中ODM和CM之间的关联,比较高加索人群的风险.
主要方法:
- 在四级眼科中心进行了一系列回顾性病例.
- 在一段时间内分析了148万名患者的数据.
- 确定了被诊断为ODM的患者,并审查了他们的临床数据,包括CM的存在.
主要成果:
- 发现ODM的患病率为0.014% (占148万患者中的213).
- 单边的ODM是常见的 (87%),经常涉及皮质 (100%),眼 (29%) 和V1/V2皮肤瘤 (53%).
- 19名患者 (9%) 患有CM,这表明与白人相比风险增加了1.3倍,瘤通常位于下方象限,厚度约为8.3mm,基本直径约为14.0mm.
结论:
- 胸腔黑色素瘤虽然很少见,但与眼部 (皮肤) 黑色素细胞瘤有关,亚洲印第安人比白人有更高的风险.
- 定期的眼科检查对于早期诊断和管理ODM患者的胸腔黑色素瘤至关重要.
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