透皮精子采集技术:一种可靠和有效的精子采集程序,用于ICSI在患有阻塞性精子缺血症的患者
Thiago P Furtado1, Andrea Kauffman Zeh2, Marcelo H Furtado2,3
1University of California, Los Angeles, USA.
JBRA assisted reproduction
|December 26, 2024
概括
皮肤取精子的技术,如PESA和TESA是可靠和有效的ICSI,即使在重复尝试. 这些方法提供了良好的生殖结果,为生育治疗提供了保证.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 不孕症治疗 不孕症治疗
背景情况:
- 阻塞性阿佐精子症在男性不孕症中构成了重大挑战.
- 穿皮精子提取为获得辅助生殖技术的精子提供了一种最小侵入性的选择.
- 了解重复采集精子程序的可靠性对于患者管理至关重要.
研究的目的:
- 为了评估皮肤性精子采集 (PESA) 的可靠性和有效性,有或没有TESA.
- 为了比较第一次和重复的检索尝试之间的精子检索和生殖结果.
- 评估PESA/TESA在细胞内精子注射 (ICSI) 的整体成功情况.
主要方法:
- 对123名患有阻塞性亚精子症的患者进行了回顾性分析,这些患者接受了PESA +/- TESA.
- 患者进行第一次精子采集与随后的采集之间的结果比较.
- 评估精子回收率和关键生殖参数 (受精,怀孕).
主要成果:
- 在所有157次尝试中实现了100%的累积精子提取率,无论之前的程序如何.
- 临床怀孕率在第一次检索时为33.3%,重复检索时为51.7%.
- 两组之间的受精率,分娩率或生化妊娠率没有显著差异.
结论:
- 带有或没有TESA的PESA是ICSI精子采集的可靠和有效策略.
- 重复的PESA程序显示出一致的可靠性,并且不会对生殖结果产生负面影响.
- 这种技术为男性不孕症治疗提供了有价值和令人放心的选择,特别是在资源有限的环境中.
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