在人类胆管性淋巴激素 (hCG) 给药当天血清孕激素的升高是否会降低活产率?
概括
人体胆性淋巴激素 (HCG) 给药当天血清孕激素的升高与体外受精 (IVF) 周期中怀孕和活产率的降低有关. 即使考虑到其他因素,这种趋势仍然存在.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 在体外受精 (IVF)
背景情况:
- 血清孕激素升高对体外受精 (IVF) 结果的影响尚未完全理解.
- 孕激素在准备子宫内膜以进行植入方面发挥着至关重要的作用.
研究的目的:
- 为了调查在人体胆固醇激素 (HCG) 给药当天血清孕激素水平升高与试管婴儿中怀孕/活产率之间的关联.
- 综合当前的文献,并提供有关此主题的数据.
主要方法:
- 现有文献的小型综述.
- 包括来自作者机构的原始数据.
- 血清孕激素水平在HCG给药当天的分析.
主要成果:
- 观察到妊娠和活产率下降的趋势,在HCG给药当天血清孕激素水平上升.
- 这种关联即使经过对潜在的混因素进行调整后也仍然显著.
结论:
- 在HCG施用之日血清孕激素升高似乎对试管婴儿成功率产生负面影响.
- 大多数研究调查这种现象报告一致的结果,表明有害影响.
相关概念视频
Gonadal and Placental Hormones
1.2K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
1.2K
Ovarian Cycle
684
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
684
Hormonal Regulation of the Menstrual Cycle
181
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
181


