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人类calpain-3及其结构可塑性:在结合titin上将同质合体分解成二元体

Qilu Ye1, Amy Henrickson2, Borries Demeler2

  • 1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.

The Journal of biological chemistry
|December 26, 2024
PubMed
概括

卡尔帕因-3,在骨肌肉中丰富,形成不活跃的六合体,在结合丁时分离成活跃的二合体. 这种结构性洞察力有助于理解由calpain-3突变引起的四肢腰带肌肉衰变.

关键词:
头部疼痛 (calpain) 是一种疼痛.卡尔帕因-3是一种疼痛.冷电子显微镜的使用方法多元化的多元化.蛋白质复合体是一种蛋白质复合体.这就是Titin Titin.

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