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对 lysophosphatidic 酸受体 1 与不同 G 蛋白的接触的结构性见解

Shota Suzuki1, Kotaro Tanaka2, Akiko Kamegawa1

  • 1Advanced Research Initiative, Institute of Integrated Research, Institute of Science Tokyo, 1-5-45 Yushima Bunkyo-ku 113-8510, Tokyo, Japan.

Journal of structural biology
|December 26, 2024
PubMed
概括

对G蛋白对 lysophosphatidic acid (LPA) 受体的合选择性的结构洞察力揭示了不同的构造. 这些发现解释了LPA受体如何与不同的G蛋白相互作用,影响细胞信号通路.

关键词:
低温电子显微镜的使用方法内皮分化基因家族内皮分化基因家族G-蛋白结合受体 (GPCR) 是一种GTP 结合蛋白质的结合蛋白质Lysophosphatidic 酸 (LPA) 是一种类型的酸.接收器 接收器 接收器斯芬哥辛-1-酸盐 (S1P) 是一种

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