在结直肠癌中神经系统
Chunjie Xu1, Chunhui Jiang1, Yuan Tian1
1Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, Shanghai, China.
Cancer letters
|December 26, 2024
概括
癌症神经科学探索瘤如何与神经系统相互作用. 本综述详细介绍了结直肠癌 (CRC) 中的瘤神经相互作用,影响其进展.
科学领域:
- 神经科学是一个神经科学.
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 恶性瘤是涉及神经系统的复杂系统性疾病.
- 癌症神经科学研究瘤与神经系统的相互作用.
- 胃肠道由外周,肠道和中枢神经系统调节,容易发生神经调节失衡,导致结肠直肠癌 (CRC) 等疾病.
研究的目的:
- 审查癌症神经科学的基本知识.
- 阐明CRC中瘤神经相互作用的机制.
- 突出神经系统在CRC发展和进展中的作用.
主要方法:
- 关于癌症神经科学和CRC的文献综述.
- 对胃肠道中神经调节机制的分析.
- 检查直接和间接的瘤神经相互作用.
主要成果:
- 瘤神经相互作用直接影响CRC细胞.
- 这些相互作用间接调节瘤微环境 (微生物群,免疫力,新陈代谢).
- 高级神经中心 (压力,情绪,认知) 也影响CRC的发生和进展.
结论:
- 神经系统在CRC中起着至关重要的作用.
- 了解瘤神经相互作用对于CRC管理至关重要.
- 癌症神经科学为CRC病原和潜在的治疗策略提供了洞察力.
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