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对测量抗血栓治疗在48小时内因缺血性中风治疗的审计进行系统审查和元分析

Andy Lim¹, Grace Phillips², Warren Chan²

¹Stroke and Aging Research Group, Department of Medicine, Monash University, Melbourne, Australia; Department of Emergency Medicine, Monash Medical Centre.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

|December 26, 2024

概括

对缺血性中风的早期抗血栓药物治疗得到了研究的支持,但大多数国家没有达到及时分娩的85%门. 这一元分析显示,在48小时内接受抗血小板治疗的患者的全球聚合比例为81.1%.

科学领域:

神经学神经学
心脏病学心脏病学
公共卫生公共卫生

背景情况:

临床试验支持早期抗血栓药物治疗缺血性中风和短暂缺血性发作.
根据北美"与指南相处"中风计划 (85%) 定义的最佳输送值,在全球范围内并未始终达到.

研究的目的:

确定在缺血性中风发作后48小时内接受抗血小板治疗的患者的综合比例.
评估全球遵守早期抗血栓治疗指南的情况.

主要方法:

在PubMed的系统文献搜索中 (截至2022年11月),确定了45项研究.
采用多层随机效应元分析,按国家分组研究,分析来自1,178,595名患者的数据.
关键词包括"中风"",审计"",抗血栓剂"",国家"和"注册".

主要成果:

在48小时内接受抗血栓治疗的患者的综合比例为81.1% (95% CI 74.5,87.8).
观察到很高的异质性,受国家内部和国家间变化的影响.
高收入国家和低收入到中等收入国家之间没有发现显著差异,但当代研究 (≥2008) 显示的比率更高 (86.5%) 与早期 (69.9%) 相比.

结论:

大多数国家在缺血性中风患者中未达到早期抗血小板治疗的85%门.
尽管随着时间的推移有所改善,但全球对推的早期治疗的坚持仍然不够理想.
需要进一步努力,在全球范围内加强及时服用抗血栓性药物.

关键词:

抗血小板药物可以抗血小板.这是一种抗血栓性抗体.亚司匹林是一种阿司匹林.国家国家国家国家.人类人类人类.一次性中风,中风.

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