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在意大利东北部从肉和牛奶中分离出来的金黄色葡萄球菌的流行率和特征
Debora Pinamonti1, Marisa Manzano1, Michela Maifreni1
1University of Udine, Department of Agricultural, Food, Environmental and Animal Science, 33100 Udine, Italy.
Journal of food protection
|December 26, 2024
概括
这项研究在意大利生肉和牛奶中发现金黄色葡萄球菌 (S. aureus),具有显著的抗生素耐药性和生物膜形成. 这些食源性病原体由于毒性因素和潜在的治疗失败而构成威胁.
科学领域:
- 食品安全 食品安全
- 微生物学 微生物学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 金黄色葡萄球菌是一种常见的食品污染物.
- 黄金菌的抗生素耐药性是一个日益严重的公共卫生问题.
- 食品中的致病性黄金菌株对消费者构成风险.
研究的目的:
- 确定意大利在生肉和牛奶中S. aureus的流行情况.
- 评估这些菌株的抗生素耐药性概况和生物膜产量.
- 评估S. aureus分离物的毒性因子和粘附能力.
主要方法:
- 从原肉和牛奶样本中分离和识别金黄色细菌.
- 对抗微生物敏感性测试和检测耐甲林黄金色杆菌 (MRSA).
- 对生物膜形成,毒性因子和粘附于Caco-2细胞的评估.
主要成果:
- 黄金色杆菌在肉和牛奶中普遍存在,具有显著的抗西林和 gentamycin 耐药性.
- 在5.71%的牛奶和25%的肉类分离物中检测到抗甲素黄金色杆菌 (MRSA).
- 大多数分离物体表现出生物膜形成和病毒性因子,具有显著的粘附能力到肠道细胞.
结论:
- 意大利的食源性金黄色细菌分离体显示出令人担忧的抗生素耐药性和毒性水平.
- 这些菌株在原始动物产品中的存在对公众健康构成重大风险.
- 病毒性因素增强了病原性,可能导致消费者抗生素治疗失败.
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