结肠直肠多的冷或热内镜粘膜切除:随机对照试验的元分析
Aamir Saeed1, Saira Yousuf1, Nicholas Noverati2
1Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Gastrointestinal endoscopy
|December 26, 2024
概括
与热EMR相比,结直肠多瘤的冷内镜粘膜切除 (EMR) 显示出较低的出血和穿孔风险,但复发性瘤的风险更高.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 对结直肠多瘤冷内镜粘膜切除 (EMR) 的兴趣日益增长.
- 需要对冷与热EMR技术进行比较分析.
研究的目的:
- 为了比较冷EMR与热EMR在结肠直肠多瘤的疗效和安全性.
- 评估结果,包括复发性瘤,切除完整性和不良事件.
主要方法:
- 随机对照试验的元分析.
- 在2024年10月之前对多个数据库进行系统审查.
- 使用随机效应模型组合风险比率 (RRs) 和95%置信区间 (CI).
主要成果:
- 感冒EMR的复发性或残留性瘤的发生率明显更高 (RR, 2.03).
- 感冒EMR显示出明显较低的延迟出血率 (RR,0.42) 和穿孔率 (RR,0.13).
- 在其他评估结果中没有发现显著差异.
结论:
- 寒冷EMR提供了延迟出血和穿孔的风险降低.
- 热EMR可能与复发性或残留性瘤的风险较低有关.
- 冷热EMR之间的选择取决于这些特定风险的平衡.
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