在重症监护室出院前使用心率预测心力衰竭患者的死亡率的有效性:来自MIMIC-IV数据库的回顾性队列研究
Chia-Ying Hsiao1,2, Min-I Su2,3,4, Yu-Cheng Chang5,6
1Department of Internal Medicine, Division of Nephrology, Taitung MacKay Memorial Hospital, Taitung, Taiwan.
BMJ open
|December 26, 2024
概括
重症心力衰竭 (HF) 患者在重症监护室 (ICU) 退院后心率升高与不良结果有关. 心率超过每分钟90次的患者面临更高的死亡率和再入院风险.
科学领域:
- 心脏病学 心脏病学
- 关键护理医学 关键护理医学
- 健康 结果 研究 研究 结果
背景情况:
- 心率是心力衰竭 (HF) 患者的一个关键预后指标.
- 从重症监护室 (ICU) 出院的严重病情的HF患者可能心率升高.
- 这种心率升高可能与不良的临床结果有关.
研究的目的:
- 调查ICU出院时心率与严重心力衰竭患者的不良结果之间的关联.
- 为了确定心率升高是否预测住院死亡率,总死亡率和ICU再入院.
主要方法:
- 一项回顾性队列研究使用医学信息中心的密切护理IV (MIMIC-IV) 数据库 (2008-2019) 的数据进行.
- 从76,943个ICU住院中,包括2365名心力衰竭患者.
- 进行了统计分析,包括多变量分析,以评估ICU出院心率和结果之间的相关性.
主要成果:
- 重症监护室出院的心率显著预测了住院死亡率 (HR 1.032),总死亡率 (HR 1.008) 和重收 (HR 1.018).
- 患有ICU出院心率>90bpm的患者在医院内死亡率 (HR 2.639),总死亡率 (HR 1.342) 和ICU再入院率 (HR 1.781) 显著上升.
- 平均ICU出院心率在幸存者和非幸存者之间对于住院死亡率 (83.56与93.84bpm,p<0.001) 有显著差异.
结论:
- 在ICU出院时心率升高 (>90bpm) 是心力衰竭患者不良结果的重要预测因素.
- 这些发现表明,ICU出院时的心率是有价值的预后标志物.
- 在ICU出院时监测和潜在地管理心率可能会改善严重病情的HF患者的结果.
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