通过皮肤输送天然产品来预防亚托邦皮肤炎
Minghui Li1, Yihua Xu2, Yanan Yu1
1Department of Pharmacy, Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo 315010, China.
天然产品提供有前途的亚托皮炎 (AD) 治疗方法,但溶解性差限制了它们的使用. 通过皮肤递送药物系统 (TDDS) 提高天然产品的透率和有效性,以改善AD管理.
科学领域:
- 皮肤病学和制药科学 皮肤病学和制药科学
- 自然产品化学 自然产品化学
- 药物输送系统 药物输送系统
背景情况:
- 亚托皮炎 (AD) 是一种慢性炎症性皮肤疾病.
- 由于安全性和可用性,在AD治疗中探索天然产品.
- 挑战包括自然化合物的溶解性,稳定性和皮肤透性差.
研究的目的:
- 审查通过皮肤递送药物系统 (TDDS) 的天然产品在亚托皮炎治疗.
- 专注于TDDS如何增强皮肤透和自然剂的积累.
- 用先进的传递方法为治疗阿尔茨海默病和其他皮肤疾病提供见解.
主要方法:
- 关于TDDS和AD天然产品的科学文献的审查.
- 对各种TDDS平台的分析:水凝,微针 (MN),脂质体,纳米乳液.
- 对研究的评估,重点是通过TDDS通过皮肤透和自然药物的积累.
主要成果:
- TDDS显著提高了天然产品的可溶性,稳定性和皮肤透性.
- 水凝,MN,脂质体和纳米乳液证明了自然化合物的增强输送.
- 增加的皮肤透和自然剂的积累导致治疗效果的改善.
结论:
- TDDS在克服AD治疗天然产品的局限性方面是有效的.
- 优化的TDDS配方可以提高皮肤病自然疗法的疗效和安全性.
- 本综述强调了TDDS在推进基于天然产品的皮肤病治疗方面的潜力.
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