肌肉交感神经活动与血清脂肪酸结合蛋白4在休息状态和在同度握手运动期间的关系
Tadayuki Hirai1, Takuto Hamaoka1,2, Hisayoshi Murai1,3
1Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Physiological reports
|December 26, 2024
概括
运动期间肌肉交感神经活动 (MSNA) 的增加与健康人群的血清脂肪酸结合蛋白4 (FABP4) 水平的增加有关. 休息的FABP4没有显示这种关联.
科学领域:
- 心血管生理学心血管生理学
- 代谢调节 代谢调节 代谢调节
背景情况:
- 脂肪酸结合蛋白4 (FABP4) 与心血管疾病有关,血清含量升高.
- 血清FABP4与交感神经系统活动之间的联系尚不清楚.
研究的目的:
- 为了研究交感神经活动和血清FABP4水平之间的关系.
主要方法:
- 21名健康的受试者接受了同度握手练习.
- 监测肌肉交感神经活动 (MSNA),心率和血压.
- 血清FABP4水平在休息和运动高峰时被测量.
主要成果:
- 同度握手运动显著增加了MSNA,心率和缩血压.
- 运动期间血清FABP4水平的变化与MSNA的变化有很强的相关性.
- 静止FABP4水平与MSNA或其他测量参数之间没有发现相关性.
结论:
- 在健康个体的急性炼期间,Efferent同情驱动可能会影响FABP4水平.
- 要确认这些发现,需要对同情活动高的人群进行进一步的研究.
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