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在接受桃体切除术的儿童中评估复发性发烧
Mana Espahbodi1,2, Kathryn M Edwards3, Steven L Goudy2,4
1Department of Otolaryngology-Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.
BMC pediatrics
|December 26, 2024
概括
在接受桃体切除术的儿童中,复发性桃体炎症状与PFAPA综合征重叠. 许多患有复发性桃体炎和发烧的儿童在桃体切除术后表现出改善.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 儿童传染病 儿童传染病
- 临床免疫学临床免疫学
背景情况:
- 回复性桃体炎是儿童桃体切除术的常见原因.
- 复发性桃体炎和PFAPA综合征 (周期性发烧,口腔口炎,喉炎和宫腺炎) 之间存在表型重叠.
研究的目的:
- 在接受桃体切除术的儿童中描述与PFAPA综合征相关的症状.
- 在评估桃体切除术的儿童中识别PFAPA的临床症状.
主要方法:
- 在范德比尔特儿童医院对接受桃体切除术的儿童的父母/监护人的前性调查.
- 在桃体切除术后3个月和12个月,通过初始和后续问卷收集关于复发性发烧症状的数据.
主要成果:
- 82%的患者参与了;33%的患者有复发性桃体炎作为桃体切除术的指示.
- 11%的人每年报告≥6次刻板体发烧发作,伴有桃体炎,宫腺炎或口腔炎.
- 患有≥3次发烧性桃体炎发作/年的儿童患有复发性口腔的患病率更高.
- 所有参与者,包括那些有复发性发烧的人,在桃体切除术后的一年内报告了较少的发烧性桃体炎发作.
结论:
- 一部分接受桃体切除术的儿童表现出与PFAPA综合征重叠的症状.
- 儿科医生和耳鼻喉科医生应在评估进行桃体切除术的儿童中识别PFAPA临床症状.
- 对这些患者可能需要进一步评估和量身定制的治疗方法.
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