体温与败血症患者全因死亡率之间的关联:分析MIMIC-IV数据库
1Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China. zhaoyunuoscu@gmail.com.
European journal of medical research
|December 26, 2024
概括
进入ICU的败血症患者的低温与28天死亡率的增加有关. 正常或高体温并没有显著影响败血症患者的结果.
科学领域:
- 关键护理医学 关键护理医学
- 败血症的研究研究.
- 热调节 热调节 热调节
背景情况:
- 异常的体温 (发烧/低温) 是影响预后的严重败血症症状.
- 温度的变化需要对败血症患者进行精细的管理策略.
研究的目的:
- 为了研究最初体温与败血症患者的临床结果之间的关系.
- 分析低温,高温和高温对死亡率的影响.
主要方法:
- 使用MIMIC-IV数据库来获取败血症患者数据 (35,499名患者).
- 使用限制立方线 (RCS) 和倾向得分匹配 (PSM) 进行分析.
- 使用考克斯和后勤回归模型评估28天,ICU和住院死亡率.
主要成果:
- 在体温和死亡率之间观察到U形关系.
- 低温 (<36°C) 与高温 (>38°C) 相比,与明显更高的死亡率有关.
- 高温症在年轻患者 (<65岁) 中显示出对死亡率的保护作用,但在老年患者中没有.
结论:
- 在ICU入院后24小时内峰值温度<36°C与28天败血症死亡率的增加有关.
- 在正常热和高热性败血症患者之间没有发现显著的预后差异.
相关概念视频
Increased Body Temperature
611
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
611
Factors Affecting Body Temperature
3.5K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
3.5K
Assessing Body Temperature - Temporal Artery
490
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's...
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's...
490
Decreased Body Temperature
573
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
573
Assessing Body Temperature - Axilla
558
Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
558
Assessing Body Temperature - Rectal
2.5K
Rectal temperature measurement is considered the most precise method for assessing core body temperature and typically registers higher than oral temperature. For adults, the rectal thermometer should be inserted 1 to 1.5 inches into the rectum to obtain the most accurate reading.
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
2.5K


