年龄对骨感应幅度调节cVEMP时间调节转移功能的影响
Raghav H Jha1, Erin G Piker2, Christopher G Clinard2
1School of Communication Sciences and Disorders, University of Memphis, Memphis, Tennessee, USA.
Ear and hearing
|December 27, 2024
概括
衰老显著降低了振幅调节的宫前置唤起肌能潜能 (AMcVEMPs),影响前置功能评估. 这项研究揭示了AMcVEMP振幅,SNR和PC在调制频率的年龄相关下降.
科学领域:
- 神经科学是一个神经科学.
- 静脉系统研究研究
- 听力学 听力学是指听力学.
背景情况:
- 宫前庭唤起肌源性潜能 (cVEMPs) 通过囊状刺激来评估前庭功能.
- 振幅调节cVEMPs (AMcVEMPs) 提供了详细的洞察力前庭结合反射.
- 在AMcVEMPs中,与年龄相关的变化仍然在很大程度上没有被描述.
研究的目的:
- 调查衰老对AMcVEMPs的影响.
- 分析 AMcVEMP 振幅,信号与噪声比 (SNR) 和相位连贯性 (PC) 上的年龄相关影响.
- 检查AMcVEMP响应在广泛的调制频率 (MFs) 的范围.
主要方法:
- 包括年轻人 (20-39岁),中年 (40-59岁) 和老年 (60-75岁) 的成年人.
- 使用振幅调制的音调 (500 Hz 载波, 11-397 Hz MF) 作为刺激.
- 记录了来自大骨肌的AMcVEMPs,并使用FTT与振幅,SNR和PC指标进行分析.
主要成果:
- AMcVEMP波形显示周期性匹配刺激MFs.
- 观察到与年龄相关的AMcVEMP振幅,SNR和PC显著下降.
- 与老年人相比,年轻成年人在更广泛的MF范围内表现出强有力的反应,减少了时间调制转移功能 (TMTF).
结论:
- 老龄化显著影响AMcVEMP反应,尽管在各个措施或MF中不均.
- 随着年龄的增长,AMcVEMPs的TMTF会变得平坦和狭窄.
- 这些发现有助于更好地了解与年龄相关的前体系统变化以及AMcVEMP的临床潜力.
相关概念视频
Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Perception of Sound Waves
4.4K
The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
4.4K
The Cochlea
44.5K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
44.5K


