在印度西部肺结核患者中感知到的社会支持和药物剂量中断:一个跨部门研究
Nirmal Ahuja1, Ashley Kuzmik2, Kristin Sznajder3
1School of Behavioral Sciences and Education, Penn State Harrisburg, Middletown, USA.
Cureus
|December 27, 2024
概括
印度的结核病 (TB) 患者的低社会支持显著增加了药物剂量中断的风险. 加强社会支持对于改善结核病治疗的坚持和结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战,特别是在印度,许多患者未能完成治疗.
- 社会支持被认为对慢性疾病的药物坚持至关重要,但其在印度结核病治疗中的作用尚未得到充分研究.
- 印度的有限研究探讨了肺结核患者感知到的社会支持和药物不服药之间的联系.
研究的目的:
- 调查印度西部肺结核患者感知到的社会支持与药物剂量中断之间的联系.
- 在社会支持中确定影响治疗坚持的特定因素.
- 为结核病管理中以患者为中心的策略提供证据.
主要方法:
- 一项涉及印度马哈拉施特拉邦比万迪市直接观察治疗,短期 (DOTS) 中心477名肺结核患者的横截面研究.
- 数据收集包括药物剂量中断,临床特征和感知到的社会支持.
- 使用了描述性和推断性统计分析,包括调整的赔率比率 (aOR).
主要成果:
- 低感知社会支持与错过结核病药物剂量增加的可能性显著相关.
- 具有较低社会支持的参与者错过剂量的可能性是2.6倍 (aOR = 2.6).
- 较低的家庭支持显示出更强烈的关联,患者错过剂量的可能性是4.1倍 (aOR = 4.1).
结论:
- 感知到的社会支持是影响肺结核患者服用药物的关键因素.
- 医疗保健战略应整合社会支持系统,以提高治疗完成率.
- 这些发现可以为决策者制定以患者为中心的干预措施,包括社交网络和家庭动态,以控制结核病提供信息.
相关概念视频
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis
Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...


