中子捕获疗法的当前研究趋势和热点:一个图书识别和可视化分析
Yuyang Cong1, Muyasha Abulimiti2, Yoshitaka Matsumoto2
1Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Frontiers in oncology
|December 27, 2024
概括
图书统计分析显示,中子捕获疗法 (BNCT) 研究在过去三十年中显著增长. 未来的方向包括新的载体,基于加速器的来源,以及扩大癌症治疗的临床应用.
科学领域:
- 医学物理 医学物理
- 放射疗法是一种放射治疗.
- 生物医学工程 生物医学工程
背景情况:
- 中子捕获疗法 (BNCT) 是一种先进的辐射疗法.
- 在过去的三十年里,BNCT的研究已经显著发展.
研究的目的:
- 进行中子捕获疗法 (BNCT) 的文献分析.
- 确定BNCT的趋势,当前的研究热点和未来的方向.
主要方法:
- 从1975年到2023年对出版物的图书统计分析.
- 数据从科学网络核心集合中获取.
- 使用VOSviewer,R和CiteSpace进行可视化和分析.
主要成果:
- 确定了3347个出版物,在1992年出现了激增.
- 日本和美国是最具生产力的国家.
- 关键的研究领域包括碳,甲,质母细胞瘤和药物输送.
结论:
- BNCT的研究已经大幅扩大,重点是新型载体.
- 未来的研究可能涉及验证BNCT模式,探索基于加速器的中子源,并扩大临床应用.
- 预计将继续开发用于癌症治疗的输送剂.
相关概念视频
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Cancer Therapies
7.4K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.4K
Positron Emission Tomography
3.9K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
3.9K
The Nucleolus
8.6K
The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...
8.6K


