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Updated: Jun 4, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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作为高度强大的KPC抑制剂的2-碳氧基诺林酸

Zheng Ma1, Ge Cui1, Lijie Dou1

  • 1State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, P.R. China.

ChemMedChem
|December 27, 2024
PubMed
概括

研究人员发现了新型的2 - 碳基诺林玻酸,可以抑制Klebsiella pneumoniae carbapenemase (KPC). 化合物1e有效地对抗KPC-2耐药性,恢复抗生素对抗耐药性Klebsiella pneumoniae的疗效.

关键词:
抗生素耐药性 抗生素耐药性碳烯质量质量问题抑制剂抑制剂的使用这就是β-乳酸酶.

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