持久性慢性牙周病作为心血管疾病的危险因素:全国性基于人口的队列研究
Jung-Hyun Park1, Gwang Hyun Leem2, Jin-Woo Kim1
1Department of Oral and Maxillofacial Surgery, Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Journal of clinical periodontology
|December 27, 2024
概括
持续性牙周病 (PD) 显著增加了心血管疾病 (CVD) 的风险. 改善或预防PD可以降低心血管疾病发生率,强调PD管理对心血管健康至关重要.
科学领域:
- 心血管健康 心血管健康
- 牙周医学 牙周医学
- 公共卫生流行病学 流行病学
背景情况:
- 牙周病 (PD) 和心血管疾病 (CVD) 之间确立的关联.
- 关于PD状态的变化如何影响心血管疾病风险的有限的大规模数据.
研究的目的:
- 调查牙周病 (PD) 的动态与发生心血管疾病 (CVD) 的风险之间的关联.
主要方法:
- 对来自韩国国家医疗保险服务的1,242,570名参与者的分析,2003年进行了口腔健康检查,2005-2006年进行了后续检查.
- 根据PD状态的变化对参与者进行分类:缺席,改善,发病和持续.
- 利用考克斯的比例危险模型来评估复合心血管疾病结果 (死亡,心肌梗塞,中风) 的危险比率.
主要成果:
- 在14.4年的时间里,6.4%的人经历了复合心血管疾病事件.
- 持久性PD与最高的心血管疾病风险相关 (HR: 1.04).
- 与持久性PD组相比,PD改善 (HR:0.97) 和PD发病 (HR:0.94) 组的CVD风险明显较低.
结论:
- 牙周病 (PD) 动态是心血管疾病 (CVD) 的潜在可修改的风险因素.
- 慢性持续性PD提高了心血管疾病发病风险.
- 有效的PD管理对于心血管疾病预防策略至关重要.
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