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通过针对eIF6来将核糖体子单元封存为非活性80S,限制了线粒体退出和癌症进展

Poonam Roshan1, Aparna Biswas1, Sinthyia Ahmed1

  • 1Department of Biology, Saint Louis University, 3507 Laclede Ave, Saint Louis, MO 63103, USA.

Nucleic acids research
|December 27, 2024
PubMed
概括

细胞转化启动因子-6 (eIF6) 调节核糖体活动,影响转化,分裂和癌症. 破坏eIF6功能会增加空缺的80S核糖体,导致细胞周期缺陷并限制癌症的入侵.

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