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COVID-19感染对甲状腺功能状态和甲状腺功能低下门诊患者的临床指数的影响
Bingxin Li1, Xiaoyun Feng1, Yihan Zhang1
1Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghais, China.
Virulence
|December 27, 2024
概括
在低甲状腺患者中,COVID-19感染会影响甲状腺功能. 哈西莫托甲状腺炎 (HT) 患者的TSH降低和FT3增加,而非HT患者的FT3增加. 接种疫苗有助于甲状腺的稳定.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 上海的Omicron变种激增是随着COVID-19控制策略的变化而发生的.
- 甲状腺功能低下症的管理需要在病毒爆发期间仔细考虑.
- 了解SARS-CoV-2对甲状腺功能的影响对于患者护理至关重要.
研究的目的:
- 为了研究COVID-19感染对低甲状腺患者甲状腺功能的影响.
- 为了比较由 Hashimoto 甲状腺炎 (HT) 和其他原因引起的甲状腺功能低下之间的结果.
- 评估SARS-CoV-2疫苗接种在维持甲状腺稳定的作用.
主要方法:
- 在上海中央医院的COVID-19感染的甲状腺功能低下门诊患者的回顾性分析.
- 患者被分为哈西莫托甲状腺炎 (HT) 和非HT组.
- 甲状腺功能测试 (TSH,FT3) 和血红蛋白水平在感染前和感染后的30天和90天评估.
主要成果:
- 在HT患者中,感染后观察到TSH显著下降,FT3和血红蛋白增加.
- 非HT患者在感染后30天显示FT3水平显著增加.
- 失活的SARS-CoV-2疫苗接种与保护甲状腺功能稳定性有关.
结论:
- 在甲状腺功能低下患者中,COVID-19感染会改变甲状腺激素水平,在HT和非HT组中具有不同的模式.
- 在低甲状腺患者的COVID-19感染期间,监测甲状腺功能和血红蛋白非常重要.
- 在这种人群中,SARS-CoV-2疫苗接种似乎有利于维持甲状腺功能稳定.
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