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Updated: Jun 4, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
11:51

Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

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基于远程H/D和C/C歧视的亚特罗皮索米基纳-4-one衍生物的合成

Yuka Watanabe1, Utae Take1, Ryunosuke Senda1

  • 1Chemistry and Materials Program, College of Engineering, Shibaura Institute of Technology, 3-7-5 Toyosu, Kohto-ku, Tokyo 135-8548, Japan.

The Journal of organic chemistry
|December 27, 2024
PubMed
概括

研究人员合成了新型的同位素亚特罗皮索米克quinazolinones. 这些化合物由于远程H / D和C / 13C歧视而表现出光学旋转,由NMR和HPLC证实.

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Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
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