在高血压患者中,通过光学一致性断层扫描评估的短期血压变化和胸膜-视网膜厚度之间的关系
Caterina Carollo1, Maria Vadalà2, Marta Ferrara1
1Unit of Nephrology and Dialysis, Hypertension Excellence Centre, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), Università di Palermo, 90128 Palermo, Italy.
Journal of personalized medicine
|December 27, 2024
概括
短期血压变化 (BPV) 与高血压患者的胸膜厚度降低有关. 具体来说,白天静脉血压的平均真实变化独立地预测了较薄的胸膜,这表明胸膜厚度是心血管风险标志物.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 血管生物学 血管生物学
背景情况:
- 高血压并发症与血压变化 (BPV) 相相关,而不仅仅是平均水平.
- 胸腔变化可能表明系统性血管损伤,可通过光学连贯性断层扫描 (OCT) 检测到.
研究的目的:
- 在高血压患者中调查短期BPV (STBPV) 与胆膜视网膜厚度之间的关联.
主要方法:
- 98名高血压患者接受了24小时的门诊血压监测.
- 测量的STBPV指数包括标准偏差和平均真实变化 (ARV).
- 使用Swept-Source OCT评估了胸膜和视网膜的厚度.
主要成果:
- 冠状腺厚度与所有ARV血压值呈反相关性.
- 白天透析血压的ARV与平均胆管厚度 (ChT-or) 有显著的相关性.
- 在调整为混因子后,这种关联仍然显著,特别是与中央和内部胆环有关.
结论:
- 短期BPV,特别是白天DBP的ARV,独立且负面地与胆道厚度相关.
- 冠状腺厚度是评估高血压患者心血管风险的有价值指标.
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