双语手术患者的功能性MRI:为多元化的儿科队列提供服务
Hannah E Goldstein1,2,3,4, Andrew Poliakov2,3,5, Dwight Barry6
1Departments of1Neurological Surgery.
Journal of neurosurgery. Pediatrics
|December 27, 2024
概括
儿科功能性MRI (fMRI) 有效地评估双语患者的手术,显示跨语言一致的语言区域激活. 未来的研究应该完善对不同患者群体的双语能力评估.
科学领域:
- 神经成像是一种神经成像.
- 儿科手术 儿科手术
背景情况:
- 功能性MRI (fMRI) 对于识别雄辩的皮质至关重要,以在手术期间保持功能.
- 儿科fMRI语言和记忆任务即使在临床上复杂的儿童中也是有效的.
- 现有的儿科fMRI研究主要集中在单语英语使用者身上,忽视了不同人群中其他语言 (LOE) 的日益普及.
研究的目的:
- 评估儿科fMRI对患有LOE的双语患者进行手术的疗效.
- 为了比较双语患者的语言激活,使用他们的母语LOE和英语.
- 为了评估手术规划的大脑语言表达的一致性.
主要方法:
- 在西雅图儿童医院 (2007-2021) 的手术工作组患者的回顾性审查.
- 确定具有有效口语流性的fMRI任务的患者,包括双语和LOE患者.
- 在双语患者中,LOE与英语fMRI激活的比较,重点是布罗卡和韦尔尼克的区域.
主要成果:
- 在363名患者中,63人 (17%) 是双语或仅使用LOE.
- 在18名双语患者中,16名用LOE和英语扫描显示可靠的语言兴趣区域 (ROI) 激活.
- 所有患者都表现出两种语言的激活,在横向性方面具有很高的一致性 (100%的布罗卡,94%的韦尼克),尽管激活程度有所不同.
结论:
- 儿科fMRI语言任务对于接受手术评估的双语患者是有效的.
- 在LOE和英语中语言fMRI激活通常在个体患者的横向性上一致.
- 需要更大的样本规模,改进双语能力评估和标准化的fMRI协议,以满足不同儿科患者群体的需求.
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